Crohn's disease: comparison of two high-end ultrasound-systems in quantificating Dynamic Contrast-Enhanced Ultrasound (DCE-US) of mural microvascularity

Purpose: To examine the reproducibility of conventional ultrasound (CU) and quantitative dynamic contrast-enhanced ultrasound (DCE-US) results in two different high-end ultrasound systems in patients with Crohn's disease (CD) and to correlate them with CDAI. Material and methods: We included 19 patients with ensured CD (36.8% women, 63.2% men; mean age ± SD, 43.7 ± 14.1) and wall segments thicker than 5 mm. With Siemens Acuson (S3000) and Toshiba (Aplio500) ultrasound systems we prospectively performed CU and DCE-US. CU included measurement of wall and layer thickness plus colour-coded/power-doppler after Limber…