Ictal local field potential recordings in anterior thalamus (ANT) and nucleus accumbens (NAC) in patients with temporal lobe epilepsy (TLE)
C Kluge, F Marquardt, J Voges, S Rampp, H Stefan, A Kowski, M Holtkamp, HJ Heinze, FC Schmitt · Klinische Neurophysiologie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Rationale: Deep brain stimulation (DBS) of the ANT has recently been established as a therapeutic strategy for medically refractory focal epilepsy. However, the mechanistic underpinnings of this novel treatment option are still not sufficiently understood, partly because under normal clinical conditions the analysis of propagation of epileptic activity is restricted to information derived either from surface or intracranial EEG recordings restricted to the accessible cortical structures. Methods: We had the opportunity to analyse ictal local field potentials recorded simultaneously from implanted DBS leads in bo…
