CareLit Fachartikel
Characterization of the interaction between hepatitis B virus subviral particles and dendritic cells in vitro
MM Farag, G Peschel, M Müller, K Weigand · Zeitschrift für Gastroenterologie · 2014 · Heft 08
Dokument
1113774
CareLit-ID
Jahr
2014
Publikation
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Zusammenfassung
In the sera of patients infected with hepatitis B virus (HBV), in addition to infectious particles, there is an excess (typically 1,000 – to 100,000-fold) of subviral particles (svp). It speculated that HBVsvp help the virus to prevent eradication by the immune system after infection. The HepG2.2.15 cell line is a cell culture system to produce human HBVsvp in vitro. These HBVsvp are composed mainly of the HBc and HBs proteins folded naturally. Dendritic cells (DC) are key players in the cellular immune response and have been shown to play an important role in controlling HBV infection. In this study, the aim wa…
Schlagworte
Dendritic Cells
After
Hepatitis
Cytokines
Tumor
Zeitschrift für Gastroenterologie
