Impact of adjuvant treatment for survival outcome in very elderly breast cancer patients (≥75 years)

Background: The optimal management of adjuvant breast cancer in very elderly women is controversial. There is a lack of data from clinical trials and thus a lack of guidelines. The aim of our study was to evaluate the impact of prognostic factors and therapeutic applications on survival. Methods: This unicentric study included 452 breast cancer patients aged ≥75 years who received adjuvant therapy between 2000 and 2009. Reported treatment modalities were categorized as optimal or suboptimal standard. Factors with impact on survival (disease-free [DFS], breast cancer-specific [BCSS], and overall survival [OS]) we…