Female gender, age elder than 50 years and a reduced glomerular filtration rate (eGFR) at baseline strongly predict the frequency of anemia in patients undergoing boceprevir tripl…
G Teuber, P Buggisch, H Löhr, H Steffens, M Kraus, C John, P Geyer, B Weber, T Witthöft, A Herrmann, M Hoesl, U Naumann, E Zehnter, D Hartmann, B Dreher, M Bilzer · Zeitschrift für Gastroenterologie · 2015 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background: Renal impairment together with a more pronounced anemia has recently been reported in about 5% of patients (pts) under triple therapy with boceprevir (BOC) or telaprevir (S Mauss et al., Hepatology 2014; 59:46 – 48). In the present interim analysis of the NOVUS observational study we investigated whether renal impairment at baseline or during treatment determines the frequency of anemia in patients undergoing BOC triple therapy. Methods: From April 2012 until January 2014, 536 pts with HCV G1 infection were recruited in the ongoing NOVUS study by 97 practices and hospitals in Germany. Pts were treate…
