CareLit Fachartikel
Influence of HCV on CREB gene expression and functional relevance
M Rohr, S Eisenbürger, R Bartenschlager, D Häussinger, JG Bode · Zeitschrift für Gastroenterologie · 2015 · Heft 01
Dokument
1114333
CareLit-ID
Jahr
2015
Publikation
PDF
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Metadaten
DOI
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zitierfähig
Bibliografische Angaben
Zusammenfassung
The Hepatitis C Virus is one of the leading causes of chronic liver diseases. In more than 70% HCV establishes a persistent infection. The high rate of persistency as well as the creeping course of disease, taking decades until development of overt disease, indicates that the virus must have evolved mechanisms to circumvent the antiviral host response and to modify inflammation. Moreover persistent viral replication requires the ability to utilize the infrastructure of the host cell for viral life cycle without significantly influencing its viability. The present project aims to investigate molecular mechanisms…
Schlagworte
Apoptosis
Actinomycin D
Actinomycin
ADP-Ribose
Hepatitis
Zeitschrift für Gastroenterologie
