Assessment by baseline HbA1c of key outcomes for once weekly dulaglutide versus insulin glargine, both with prandial insulin lispro, in patients with type 2 diabetes from the Asse…
O Adetunji, H Jung, N Jia, Z Milicevic · Diabetologie und Stoffwechsel · 2015 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction: Post-hoc subgroup analysis by baseline HbA1c investigating the efficacy and safety of once-weekly dulaglutide and daily insulin glargine in patients with T2DM, all receiving prandial insulin lispro (± metformin). Methods: Efficacy and safety data from patients receiving dulaglutide 1.5 mg (N = 293), dulaglutide 0.75 mg (N = 291) or insulin glargine (N = 291) were compared at 26 weeks within each baseline HbA1c subgroup (< 8.5%, ≥8.5%). Results: Baseline characteristics were similar between HbA1c subgroups. In both HbA1c subgroups, Least squares mean HbA1c decreased significantly (p < 0.001) from ba…