6-months follow-up retrospective study of posterior total (NISSEN) fundoplication patients with GERD: Influence of psychiatric co-morbidity and antidepressant co-treatment in ther…

Background: Surgical methods play a significant role in the treatment of gastroesophageal reflux disease (GERD) refractory to conservative therapy. There is no evidence-based consensus on the best choice of technique, posterior total (360o) Nissen fundoplication is the most widely used antireflux surgery technique worldwide. Therapy dependent and refractory GERD patients with psychiatric co-morbidity and/or antidepressant co-treatment araise challange in choice of best treatment methods. Aim of the study was to compare 6-month-results of Nissen fundoplication of psychiatric co-morbidity (PCM, n = 16) and antidep…