CareLit Fachartikel
Influence of the microbiome in regulating ConA-induced-liver injury
B Schiller, C Wegscheid, AK Horst, G Tiegs · Zeitschrift für Gastroenterologie · 2015 · Heft 12
Dokument
1115327
CareLit-ID
Jahr
2015
Publikation
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Metadaten
DOI
ja
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Zusammenfassung
Introduction: The liver is continuously exposed to gut derived factors and bacteria. It has been shown, that gut microbiota might be involved in liver diseases such as non-alcoholic fatty liver disease, hepatic encephalopathy, as well as viral, and alcoholic hepatitis. Nevertheless, little is known about the influence of gut microbiota on immune-mediated liver injury. The role of gut microbiota in Concanavalin A (ConA)-induced T-cell mediated hepatitis was investigated in antibiotic treated mice. Materials and Methods: Mice were treated with antimicrobial drugs (Neomycin, Bacitracin, Pimaricin) for 8 days prior…
Schlagworte
Hepatitis
Concanavalin A
Bacitracin
Population
Bacteria
Zeitschrift für Gastroenterologie
