Development of De Novo Donor-specific Antibodies after Liver Transplantation with Antibody-mediated Rejection and Successful Treatment by Plasmapheresis
J Rashidi-Alavijeh, K Willuweit, HA Baba, A Paul, G Gerken, K Herzer · Zeitschrift für Gastroenterologie · 2015 · Heft 12
Bibliografische Angaben
Zusammenfassung
Background: Although donor-specific antibodies (DSAs) are known to be an important risk factor in most solid organ transplantations, leading to increased risk of humoral rejection, the role of DSAs in liver transplantation is still not clarified. Liver transplantation was thought to play an exceptional role due to tolerogenic characteristics of the liver, but this point of view is questioned in recent years, since associations of DSAs and lower transplantation outcome were frequently reported. We report on a patient with DSA-positive humoral rejection after liver transplantation. Methods: Detection of DSAs was p…