CareLit Fachartikel

Role of new pathways in liver regeneration after acute and chronic liver damage

K Behnke, PA Lang · Zeitschrift für Gastroenterologie · 2015 · Heft 12

Dokument
1115340
CareLit-ID
Jahr
2015
Publikation
PDF
nein
Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
K Behnke, PA Lang
Ausgabe
Heft 12 / 2015
Seiten
–
Erschienen: 2015-12-14 00:00:00
ISSN
0044-2771

Zusammenfassung

The liver is a vital organ that performs many biological functions (e.g. synthesis of bile and blood proteins, detoxification, glycogen storage, innate immunity). Interestingly, the liver also has a unique ability to regenerate following the loss of liver mass. Loss of at least 30% of liver mass, leads to synchronized proliferation of mature hepatocytes and rapid restoration of liver mass via compensatory hyperplasia. When a liver has recovered after chronic damage caused by e.g. viral infection the whole complex architecture of the liver must be restored. Hepatic stellate cells (HSCs) are mainly known for their…

Schlagworte

After Blood Proteins Architecture Cytokines Cytokine Blood Zeitschrift für Gastroenterologie