CareLit Fachartikel
The Hepatitis C Virus (HCV) results in an increased attraction of human neutrophils to its host cell by a basal and EGF-induced CXCR2 ligand expression
C Gröpper, R Bartenschlager, D Häussinger, JG Bode · Zeitschrift für Gastroenterologie · 2015 · Heft 12
Dokument
1115343
CareLit-ID
Jahr
2015
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: To modulate the inflammatory response of the host and to utilize host infrastructure without largely impeding viability of the infected cell HCV requires strategies to establish persistent infections and to escape antiviral immunity. Chemokines have the major function as chemoattractants to lead the migration of immune cells. HCV has evolved mechanisms to gain access to the control of these factors. The present study investigates the impact of HCV on the expression of the CXCR2 ligands CXCL1 to 3 and 8 in its host cell, the ability of EGF to induce these mediators and the biological function of the…
Schlagworte
Chemokines
Chemokine
Blood
Blood Cells
Lead
Hepatitis
Zeitschrift für Gastroenterologie
