Lactation is associated with altered metabolomic signatures in women with gestational diabetes
D Much, A Beyerlein, A Kindt, J Krumsiek, F Stückler, M Rossbauer, A Hofelich, D Wiesenäcker, S Hivner, M Herbst, W Römisch-Margl, C Prehn, J Adamski, G Kastenmüller, F Theis, AG Ziegler, S Hummel · Diabetologie und Stoffwechsel · 2016 · Heft 04
Bibliografische Angaben
Zusammenfassung
Aims: Lactation for > 3 months in women with gestational diabetes is associated with a considerably reduced long-term risk for type 2 diabetes that persists for up to 15 years postpartum. However, the underlying protective mechanisms are unknown. We examined whether lactation for > 3 months is associated with altered metabolomic signatures postpartum. Methods: We enrolled 197 women with gestational diabetes at a median time of 3.6 years after delivery. Targeted metabolomics profiles (including 155 metabolites) were obtained during a glucose challenge test. Information on lactation duration was collected by inter…
