CareLit Fachartikel

Detection of biomarkers in blood macrophages via EDIM blood test in nephroblastoma patients

MJ Stagno, E Schmid, S Warmann, R Handgretinger, J Fuchs · Klinische Pädiatrie · 2016 · Heft 05

Dokument
1115834
CareLit-ID
Jahr
2016
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Pädiatrie
Autor:innen
MJ Stagno, E Schmid, S Warmann, R Handgretinger, J Fuchs
Ausgabe
Heft 05 / 2016
Seiten
–
Erschienen: 2016-05-02 00:00:00
ISSN
0300-8630

Zusammenfassung

Introduction: So far, a tumor-specific marker for nephroblastoma has not been described. A sensitive and specific liquid biopsy test of diagnosing tumor occurrence within the peripheral blood could possibly contribute to an improved prognosis of affected patients. Different reactions of the immune system to tumors have been observed so far; these reactions include as a very early step phagocytosis of tumor cells by macrophages. The Epitope-Detection in Monocytes (EDIM blood test) allows detection of intracellular tumor-protein epitopes in peripheral blood macrophages after phagocytosis of tumor cells or even com…

Schlagworte

Blood Tumor Biomarkers Diagnosis Biopsy After Klinische Pädiatrie