CareLit Fachartikel
Glycolipids of house dust mites – studying the impact of allergen-lipid association
N Gonzalez Roldan, U Jappe, KA Duda · Pneumologie · 2016 · Heft 07
Dokument
1115893
CareLit-ID
Jahr
2016
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: House dust mites (HDM) are important inductors of allergic asthma. HDM and its fecal pellets consist of glycoproteins and a wide range of chemically distinct substances, including lipids, which potentially initiate and/or modulate allergic reactions. Lipids can protect allergens from degradation and enhance their cellular uptake. Several major allergens from different sources bear hydrophobic domains, thus enabling them to interact with lipids. Methods: In order to examine the role of HDM-derived lipids on the initiation of immune responses, lipid-containing molecules were obtained from Dermatophag…
Schlagworte
Allergens
Dermatophagoides pteronyssinus
Association
Chloroform
Cytokine
Asthma
Pneumologie
