Sensitization to Aspergillus fumigatus in COPD patients with and without bronchiectasis
S Everaerts, K Vermeersch, E Van Hoeyveld, B Vanaudenaerde, X Bossuyt, K Lagrou, L Dupont, W Janssens · Pneumologie · 2016 · Heft 10
Bibliografische Angaben
Zusammenfassung
The clinical impact of sensitization to Aspergillus fumigatus (Aspf) and its role in the development of bronchiectasis (BRECT) in COPD is not well understood. We scored computer tomography of the thorax for BRECT using the modified Reiff score in 300 patients with COPD. This score assesses the number of involved lobes (the lingula considered separately) and degree of dilatation (1 = tubular, 2 = varicose and 3 = cystic). Consequently 0 is the minimum and 18 is the maximum score. Furthermore we measured concentrations of total IgE, Aspf IgE (including Aspf recombinants rAsp f1-f4 and f6) and Aspf IgG by ImmunoCap…
