Differences in gene expression of eutopic endometrium from healthy women and endometriosis patients
I Beyer, R van Rensburg, S Boeddecker, JS Kruessel, T Fehm, R Gruemmer, AP Bielfeld · Geburtshilfe und Frauenheilkunde · 2016 · Heft 10
Bibliografische Angaben
Zusammenfassung
Introduction: Endometriosis is one of the most common and, yet, underdiagosed disease in reproductive age women. Patients show very divergent signs of pain from none to severe with a magnitude mostly not correlated to the extent of the disease. Additionally, endometriosis is often associated with infertility. One of the pathomechanism theories is retrograde menstruation. The underlying conditon has, however, not been revealed so far. Furthermore, endometriotic lesions outside the uterus are not explained satisfactory by the aforementioned hypothesis. Processes of neoangiogenesis, proliferation and inflammation a…