Pregnancy rates after slow release insemination: A report of two randomized controlled pilot studies and meta-analysis

Introduction: A modified application technique of intrauterine insemination is the slow release insemination (SRI), firstly described in 1992 by Muharib et al. who published higher pregnancy rates with SRI. This randomized cross-over study reported per cycle and cumulative pregnancy rates of 6.1% and 22% for standard bolus IUI, and 15.0% and 63.1% for SRI, respectively. Study design: This study reports the results of two randomized cross-over pilot studies conducted in Germany and Israel between 2004 – 2007, and a meta-analysis of all eligible studies on SRI (n = 3). Methods: Women with infertility aged between…