Intraocular Concentrations of Clindamycin Obtained by Sequential Parabulbar Injections
Harvey Lincoff, Ingrid Kreissig, Yasser Serag, Daniel Laroche · Klinische Monatsblätter für Augenheilkunde · 2000 · Heft 04(216) · S. 223-226
Bibliografische Angaben
Zusammenfassung
Summary PURPOSE To measure the intraocular concentration of Clindamycin that can be maintained by sequential injection through a retained parabulbar catheter. MATERIALS AND METHODS The peak intraocular concentration and half-life of Clindamycin after parabulbar injection was determined in a rabbit model. In a second experiment a parabulbar catheter was inserted and the maximum concentration that could be maintained by sequential injection through the catheter at intervals of 6 hours was determined. In a third experiment both eyes of the rabbit were catheterized and one infused with Clindamycin. The eyes were enu…