CareLit Fachartikel
Tuberculosis in a nine year old girl treated with Infliximab for systemic juvenile idiopathic arthritis
W Armbrust, SSM Kamphuis, TF Wolfs, TJW Fiselier, PG Nikkels, W Kuis, NM Wulffraat · Aktuelle Rheumatologie · 2003 · Heft 11
Dokument
1130925
CareLit-ID
Jahr
2003
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
A five year old girl presented in 1998 with typical features of systemic juvenile idiopathic arthritis (S-JIA). Remission was difficult to accomplish despite the use of steroids and indomethacin, later followed by high dose methotrexate (MTX), ciclosporin, methyl prednisone pulses and etanercept (0,4mg/kg twice a week). Then, high-dose infliximab (20mg/kg/month) was added in January 2002. Since 2001 she had a severe lymphopenia and decreased in vitro cellular responses to mitogens, antigens and PPD. In April 2002, fever changed from a spiking to a more continuous pattern and arthritis persisted. Infliximab was s…
Schlagworte
Arthritis
Respiratory Insufficiency
Adolescent
Diagnosis
Antigens
Blood
After
Aktuelle Rheumatologie
