CareLit Fachartikel
Expression of the novel gene osteoactivin in rat and human liver tissue and isolated liver mononuclear phagocytes
BH Haralanova-Ilieva, T Armbrust, G Ramadori · Zeitschrift für Gastroenterologie · 2004 · Heft 02
Dokument
1131260
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Jahr
2004
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Zusammenfassung
The transmembrane glycoprotein osteoactivin is found in osteoblasts, dendritic cells and tumor cells and is supposed to plays a role in osteoblast maturation and cell adhesion. Methods: Total RNA was extracted from rat organs, and from cultured liver cell populations (hepatocytes, Kupffer cells, sinusoidal endothelial cells, hepatic stellate cells, myofibroblasts), and analyzed by Northern blot hybridization. Moreover, inflammatory mononuclear phagocytes (MNP) were isolated from carbon tetrachloride (CCl4)-treated rats. Cultured Kupffer cells and MNP were treated with lipopolysaccharide (LPS) or dexamethasone (D…
Schlagworte
Kupffer cells
inflammation
osteoactivin
Dendritic Cells
Dexamethasone
Hepatitis
Tumor
Zeitschrift für Gastroenterologie
