CareLit Fachartikel
Refractory sprue: Report of 2 cases without previous history of celiac disease
T Gurbity Palfi, L Krenacs, E Bagdi, T Krenacs, K Piukovics, J Kiss · Zeitschrift für Gastroenterologie · 2004 · Heft 05
Dokument
1131559
CareLit-ID
Jahr
2004
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Zusammenfassung
Background: Refractory sprue (RS) fails to improve after a strict gluten-free diet. Intraepithelial lymphocytes (IEL) in RS show abnormal phenotype. Our report presents 2 cases of RS with no previous history of celiac disease (CD). Case reports: Case 1: 71 years old female was diagnosed and treated for anaplastic large cell lymphoma presented in an axillary lymph node. Gastroscopy biopsy performed due to profuse diarrhea revealed flat mucosa (Marsch 3c) with marked theliocytosis (10 IEL/10 epithelial cells). IEL demonstrated CD3+, CD8-, strongly suggestive of RS. PCR revealed monoclonal T-cell gene rearrangement…
Schlagworte
Diet
Biopsy
Azathioprine
Anorexia
Diarrhea
Atrophy
After
Zeitschrift für Gastroenterologie
