Cost-Effectiveness Analysis of Combination Therapy with Peginterferon and Ribavirin for Patients with Chronic Hepatitis C and Associated Diseases in the German Health Care Context
U Siebert, G Sroczynski, S Rossol, P Aidelsburger, A Conrads-Frank, JB Wong, J Wasem · Zeitschrift für Gastroenterologie · 2004 · Heft 08
Bibliografische Angaben
Zusammenfassung
Aims: Antiviral treatment (AVT) has been shown to be efficacious and cost-effective in clinical trial-based populations with chronic hepatitis C (CHC). However, comorbidity such as HIV/HCV coinfection, hemophilia, and history of i.v. drug use may impact long-term effectiveness and costs in the real world. Objective: To assess the cost-effectiveness of different AVT strategies considering comorbidity associated with CHC. Methods: Design: Cost-effectiveness analysis using a Markov model [1]. Data Sources: Pooled efficacy data from meta-analyses of randomised clinical trials, litarature-based epidemiologic data on…
