CareLit Fachartikel
Neuronal Degeneration in the Retina during Ageing and in Neurodegeneration
S Isenmann · Klinische Neurophysiologie · 2004 · Heft 08
Dokument
1131895
CareLit-ID
Jahr
2004
Publikation
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Metadaten
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Zusammenfassung
CNS neurons gradually tend to dysfunction and degenerate with increasing age. This process may to some extent be conceived as part of the physiological ageing process, and it does not necessarily lead to relevant functional impairment. Excessive, pathological neuronal degeneration, as occurs in sporadic neurodegenerative diseases such as Alzheimer's disease, may represent premature ageing and degeneration of neurons in particular brain regions and functional circuits. Alzheimer's disease is characterized by progressive dysfunction and synaptic as well as neuronal loss of cholinergic neurons in the basal forebrai…
Schlagworte
Cholinergic Neurons
Basal Forebrain
Amyloid
Lead
Amyloid-Plaques
Klinische Neurophysiologie
