Visual Connectivity in Cases with Unilateral Focal Cortical Dysplasia or Hemispherectomy in fMRI

Structural and functional changes caused by malformations of cortical development or early cortical lesions are poorly understood. Earlier brain activation studies showed that plastic reorganization and recruitment of additional cortical areas may be responsible for residual sensorimotor function. We describe two patients (one with unilateral focal cortical dysplasia, the other with right hemispherectomy), both of whom had preserved but significantly diminished object motion perception within the contralateral hemifield. FMRI during hemifield motion stimulation revealed two different types of plastic reorganizat…