Prediction of gadolinium enhancement status on MRI at baseline of multiple sclerosis trials

The aim of this study is to find predictive determinants for the occurrence of Gadolinium enhancement. Our results are expected to simplify the selection of informative patients, i.e. patients who show disease activity, at baseline of future clinical Multiple Sclerosis (MS) trials. The open portion of the unique multinational database of the Sylvia Lawry Centre for Multiple Sclerosis Research (SLCMSR) was used to investigate the role of clincial and demographic determinants on the Gadolinium enhancement status at baseline in patients eligible for randomized clinical trials (RCTs). We used multiple logistic regre…