[11C]-L-Methionine positron emission tomography in the mManagement of children and young adults with brain tumors

Background: Methyl-[11C]-L-methionine ([11C]MET) positron emission tomography (PET) is a well established method in the diagnosis and management of adult patients with brain tumors. Only a few [11C]MET-PET studies have focused on children with brain neoplasm. Because of the radiation exposure, long scan acquisition time, and the need for sedation in very young children [11C]MET-PET studies should be restricted to children with brain tumors where a clear decision for further therapy management is not possible from magnetic resonance imaging (MRI) alone. Purpose: We investigated the diagnostic accuracy of [11C]MET…