CareLit Fachartikel
Apoptosis Investigation in Liver Metastases with Precision Cut Tissue Slices (PCTS)
HU Kasper, E Konze, D Stippel, U Drebber, HP Dienes · Zeitschrift für Gastroenterologie · 2005 · Heft 01
Dokument
1132379
CareLit-ID
Jahr
2005
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Zusammenfassung
Introduction: Apoptosis induction in tumor cells, e.g. by tumor infiltrating lymphocytes (TIL), is one of the main host mechanisms for prevention and defending of cancer. Liver metastases are a frequent event in patients with colorectal carcinoma. The host defense in the liver is not yet fully understood. We used PCTS of liver metastases of colorectal carcinoma to look into the reagibility of tumor tissue to apoptotic stimuli. Methods: PCTS were prepared from 3 human liver metastases of colorectal carcinoma using Brendel Vitron Tissue Slicer and incubated submersed in supplemented RPMI medium. Apoptosis was indu…
Schlagworte
Apoptosis
PCTS
metastases
After
Tumor
Actinomycin D
Actinomycin
Zeitschrift für Gastroenterologie
