Fatty Liver Disease in Morbidly Obese Patients in Correlation to Obesity Related Co-Morbidities
AM Wolf, B Busch, U Beisiegel · Zeitschrift für Gastroenterologie · 2005 · Heft 01
Bibliografische Angaben
Zusammenfassung
Obesity is a major risk factor for fatty liver disease. The purpose of this study was to determine the degree of steatosis, inflammation and fibrosis in liver biopsies of morbidly obese patients, along with potential contributors to pathologies of serum insulin, glucose, leptin, triglycerides, HDL-cholesterol. The study population included 179 morbidly obese patients (82% females and 18% males with a mean age of 39±9 (SD) years, a BMI of 52±8kg/m2 and an excess body weight of 80±24kg). All patients were tested negative for hepatitis and HIV pre-operatively. Liver biopsies were taken intra-operatively during bari…