Prognostic markers in the histological assessment of Barrett's esophagus
I Németh, A Rosztóczy, F Sükösd, F Izbéki, G Kurucsai, J Lonovics, T Wittmann, L Tiszlavicz · Zeitschrift für Gastroenterologie · 2005 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Barrett's esophagus (BE) is considered a potential praemalignant condition. Aim: To evaluate the diagnostic efficiency of different methods in BE with dysplasia. Materials and methods: Biopsy specimens from 88 patients with endoscopic evidence of BE were analysed by HE, AB-PAS and Giemsa staining. In cases of suspected dysplasia, immunohistochemical investigations were used (Mib-1, p53, Cox-2). Results: Low-grade dysplasia was diagnosed in six patients with cardia type BE and in 15 patients with intestinal type BE. In one case of confirmed BE, adjacent squamous epithelium proved to be dysplastic. Fou…
