CareLit Fachartikel

Effects of carbamazepine and levetiracetam on gaze and posture control

K Won, F Schautzer, S Krafczyk, J Kleine, U Büttner, S Noachtar · Aktuelle Neurologie · 2005 · Heft 10

Dokument
1133099
CareLit-ID
Jahr
2005
Publikation
PDF
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Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Aktuelle Neurologie
Autor:innen
K Won, F Schautzer, S Krafczyk, J Kleine, U Büttner, S Noachtar
Ausgabe
Heft 10 / 2005
Seiten
–
Erschienen: 2005-10-26 00:00:00
ISSN
0302-4350
DOI
10.1055/s-2005-919328

Zusammenfassung

Purpose: To compare objective measures (nystagmography, posturography) of side effects of slow release carbamazepine (CBZ) and levetiracetam (LEV) on gaze and posture control. Methods: Eye movements and posture control were investigated prospectively before (baseline) and 1 hour, 4 hours and 8 hours after a single dose of 1000mg LEV and 400mg slow release CBZ in 12 healthy volunteers in a double-blind cross-over randomized trial. Results: LEV reached average maximum plasma levels of 17.6mg/l 1 hour after intake, whereas CBZ reached average maximum plasma levels of 4.8mg/l 8 hours after intake. CBZ impaired postu…

Schlagworte

After Carbamazepine Eye Movements Aktuelle Neurologie