A novel method of pain related potentials elicited by electrical stimulation of skin for early detection of diabetic small-fiber neuropathy
Z Katsarava, S Koeppen, I Kavuk, D Müller, F Sack, H.C Diener, V Limmroth, H Kaube · Aktuelle Neurologie · 2005 · Heft 10
Bibliografische Angaben
Zusammenfassung
Objective: To investigate whether pain related evoked potentials (PREP) elicited by non-invasive trans-cutaneous electrical stimulation could be useful in detection of diabetic small fiber neuropathy. Methods: We studied two groups of healthy controls ('young': N=36, 8 females, mean age=22 years, range [19–29], 'older': N=24, 14 females, mean age=46.5 years, range [30–65]) and two groups of patients with diabetes (‘with neuropathic symptoms': N=35, 15 females, mean age=52 years, range [36–64] and 'without symptoms': N=24, 8 females, range [32–64]). We included only diabetic patients without any abnormalities in…