CareLit Fachartikel

Spatial Organization and Composition of the Mucosal Flora in Inflammatory Bowel Disease–A fluorescence in situ hybridization (FISH) study

A Swidsinski · Zeitschrift für Gastroenterologie · 2006 · Heft 04

Dokument
1133153
CareLit-ID
Jahr
2006
Publikation
PDF
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Metadaten
DOI
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Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
A Swidsinski
Ausgabe
Heft 04 / 2006
Seiten
–
Erschienen: 2006-04-10 00:00:00
ISSN
0044-2771

Zusammenfassung

Aims: Bopsies from patients with IBD and controls, whole intestines for normal mice and for three models of murine colitis were investigated using FISH. Results: No adherent biofilms were present in the intestine of healthy controls. In contrast, a dense tightly adherent biofilm was detected in all IBD patients. Less abundant biofilm was also found in 60% of patients with IBS. The composition of biofilm in controls and IBD differed. Bacteroides spp. were predominant in IBD, while Eubacterium rectale was predominant in IBS. In some IBD patients, specific biofilms with mainly E.coli or Serpulina were observed. Sim…

Schlagworte

Bacteria Bacteroides Biofilms After Bacterial Adhesion Detergents Biopsy Zeitschrift für Gastroenterologie