Characterization, outcome, and prognosis in 273 patients with primary sclerosing cholangitis: a single center study
JJW Tischendorf, H Hecker, M Krüger, MP Manns, PN Meier · Zeitschrift für Gastroenterologie · 2006 · Heft 04
Bibliografische Angaben
Zusammenfassung
Background & Aims: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with varying severity and progression. This study describes the natural history of PSC patients and evaluates the prognostic significance of clinical, biochemical and cholangiographic findings constructing a novel prognostic model. Methods: A population of 273 German PSC patients were studied with a median follow up time of 76 months (range, 1–280 months). Survival curves were analyzed by the Kaplan-Meier method, and prognostic significance of clinical, biochemical and cholangiographic features recorded at the time of…