Prospective randomised comparison of mini-Laparoscopy and percutaneous liver biopsy. Analysis of 1000 examinations
UW Denzer, A Arnoldy, U Weickert, S Kanzler, PR Galle, JR Riemann, HP Dienes, AW Lohse · Zeitschrift für Gastroenterologie · 2006 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction: Percutaneous liver biopsy is the gold standard for gaining liver histology in chronic liver disease (pLB). Nevertheless false negative biopsy rates in cirrhosis range from 10–50%. Diagnostic mini-laparoscopy (optic 1.9mm) under conscious sedation (ML) has the advantage of additional macroscopic evaluation. This study compared both methods prospectively and randomised. Methods: Patients gave written informed consent. Exclusion of severe coagulation disorders. Liver biopsy: Vim Silverman needle (ML); Menghini needle (pLB) (biopsy diameter 1.4mm). Macroscopic liver evaluation documented as normal, fib…