CareLit Fachartikel

Cellular immune responses after successful hepatitis B immunization in patients transplanted for HBV-related diseases: Existence of HBsAg-specific regulatory T cells

T Bauer, M Günther, U Bienzle, W Jilg · Zeitschrift für Gastroenterologie · 2006 · Heft 01

Dokument
1133493
CareLit-ID
Jahr
2006
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
T Bauer, M Günther, U Bienzle, W Jilg
Ausgabe
Heft 01 / 2006
Seiten
–
Erschienen: 2006-01-16 00:00:00
ISSN
0044-2771
DOI
10.1055/s-2006-931738

Zusammenfassung

Patients after liver transplantation for hepatitis B related diseases are currently treated lifelong with hepatitis B immunoglobulin to prevent endogenous reinfection with hepatitis B virus (HBV). Active immunization with hepatitis B vaccine would be a preferable alternative; however, most attempts to immunize these patients with standard vaccine failed. A study with a new adjuvanted hepatitis B vaccine (HBsAg-AS02) was exceptionally successful leading to a hightitered longlasting antibody response in 80% of all vaccinees (Bienzle et al., Hepatology. 2003 Oct;38(4): 811–9). In a continuative study we analysed ce…

Schlagworte

Hepatitis After Population Cytokine Transplantation Zeitschrift für Gastroenterologie