CareLit Fachartikel
Humoral and T helper cell responses elicited by immunization with dendritic cells genetically modified with an adenoviral vector expressing HCV NS3 protein in HLA-A2.1 transgenic…
M Xiang, C Eisenbach, CM Lupu, E Ernst, W Stremmel, J Encke · Zeitschrift für Gastroenterologie · 2006 · Heft 01
Dokument
1133496
CareLit-ID
Jahr
2006
Publikation
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Metadaten
DOI
ja
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Zusammenfassung
Dendritic cells (DC) are potent antigen-presenting cells that play a critical role in the initiation of T lymphocyte response. The recombinant adenovirus (rAd) has widely been employed in gene therapy and for delivering genes into primary cell types. DCs and rAd are two highly promising vaccine components against hepatitis C virus (HCV) infection. There has been little information, however, on the advantageous immuno-stimulatory capacity by their combination into one vaccine correlating with clearance of HCV infection in animal models. Aims The present study is to investigate the potential of adenovirus for HCV…
Schlagworte
Dendritic Cells
After
Antigen-Presenting Cells
Cytokine
Hepatitis
Zeitschrift für Gastroenterologie
