CareLit Fachartikel

Variants and Differential Diagnosis of Peripheral Nerve Hyperexcitability

HJ Gdynia, AC Ludolph, AD Sperfeld · Klinische Neurophysiologie · 2006 · Heft 03

Dokument
1133635
CareLit-ID
Jahr
2006
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
HJ Gdynia, AC Ludolph, AD Sperfeld
Ausgabe
Heft 03 / 2006
Seiten
–
Erschienen: 2006-03-24 00:00:00
ISSN
1434-0275

Zusammenfassung

Aims: Peripheral nerve hyperexcitability syndromes (PNHS) are a heterogeneous group of diseases characterized by spontaneous muscle fiber activity, e.g. myokymias and fasciculations. Acquired, hereditary and idiopathic forms are known. Antibodies to voltage-gated potassium channels (VGKCs) appear likely to be the main effector mechanism in many patients with acquired PNHS. Neuromyotonia (Isaacs' syndrome when acquired), cramp-fasciculation syndrome and Morvan's disease are phenotypic variants of PNHS. Beside of idiopathic forms the association of PNHS and autoimmune diseases is well known. Furthermore medication…

Schlagworte

Diagnosis Autoimmune Diseases Autoantibodies Association Antibodies Clofibrat Klinische Neurophysiologie