CareLit Fachartikel

Structural and functional MRI correlates of cognitive impairment in patients with multiple sclerosis

K Morgen · Klinische Neurophysiologie · 2006 · Heft 03

Dokument
1133644
CareLit-ID
Jahr
2006
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
K Morgen
Ausgabe
Heft 03 / 2006
Seiten
–
Erschienen: 2006-03-24 00:00:00
ISSN
1434-0275
DOI
10.1055/s-2006-939238

Zusammenfassung

Cognitive impairment in MS is common and tends to affect executive functions, working memory and attention. The mechanisms of cognitive impairment and the significance of compensatory processes in the central nervous system (CNS) in MS-patients are not well understood. In the current study, we analyzed mildly disabled patients with relapsing-remitting MS and matched control subjects with a neuropsychological test battery, voxel-based morphometry (VBM) and functional MRI. Patients showed reduced performance compared to healthy control subjects on tests of working memory and executive function. Performance on the…

Schlagworte

Atrophy Executive Function Association Attention Affect Klinische Neurophysiologie