Smooth pursuit modification due to visual context in patients with Parkinson's disease and age-matched controls
A Straube, J Ladda, P Valkovic, T Eggert · Klinische Neurophysiologie · 2006 · Heft 03
Bibliografische Angaben
Zusammenfassung
Patients with Parkinson's disease fail to complete predictive saccades, whereas the predictive behaviour in the smooth pursuit system maintains normal. A tendency for an improvement of saccadic accuracy and smooth pursuit gain during the ON phase of treatment was described, suggesting a partially dependence of these oculomotor systems on an adequate dopaminergic state. We investigated the smooth pursuit system in 9 patients with mild to moderate Parkinson's disease comparing to 10 age-matched healthy controls. Patients were tested during OFF and ON phase of medication and controls were measured twice consecutive…