Restoration of vision with non-invasive electrical brain synchronisation after optic nerve damage

Objective: Partial visual system damage after stroke or trauma can be treated by repetitive training with visual stimuli („vision restoration therapy“, VRT). It is conceivable that improved visual functions are mediated by enhance synaptic transmission of surviving neuronal elements through LTP-like mechanisms of increased synaptic efficacy. To test this hypothesis we now studied if non-invasive repetitive stimulation of the damaged visual system with LTP-like low-level current bursts can also induce some vision restoration. Methods: 446 patients with optic nerve lesion which was caused by either traumatic brain…