Is there any specific role of the capsaicin-sensitive afferent nerves in the development of the human chronic gastritis with or without Helicobacter pylori infection?

Background: The capsaicin-sensitive afferent nerves (CSANs) take place in the development of gastric mucosal damage and/or protection in animals and in human subjects (Mózsik Gy, Abdel-Salam OME, Szolcsányi J: Capsaicin-Sensitive Afferent Nerves in Gastric Mucosal Damage and Protection. Budapest, Akadémiai Kiadó, 1997. Mózsik Gy, Rácz I, Szolcsányi J. World J Gastroenterol 11:5180–5184, 2005). The gastritis is a common appearance of the inflammation in the stomach caused by different factors (H. pylori, autoimmune mechanisms, chemical agents, NSAIDs). The aim of the study was to clarify up the role of CSANs in h…