Pulmonale Clearance: Possibilities for Pharmacotherapy
WD Bennett · Pneumologie · 2006 · Heft 07
Bibliografische Angaben
Zusammenfassung
The mucociliary clearance (MC) is a well-coordinated system consisting of airway secretory cells that produce a sol and gel (or mucus) fluid layer on the airway surface and ciliated cells that propel the mucus out of the lung towards the mouth. In health this system is very effective at clearing mucus and associated bacteria and toxins from our lungs. However, in a variety of airway diseases (e.g. chronic bronchitis (CB), asthma and cystic fibrosis (CF)) this system becomes dysfunctional leading to further exacerbation of airway inflammation and an increasing reliance on cough clearance to remove secretions from…