CareLit Fachartikel
Extent of hepatic parenchymal chimerism after liver transplantation
O Dirsch, J Bohr, H Chi, U Dahmen · Zeitschrift für Gastroenterologie · 2006 · Heft 09
Dokument
1134218
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Jahr
2006
Publikation
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Zusammenfassung
Introduction: Hematopoietic stem cells are able to “transdifferentiate“ into parenchymal cells, however the regulation of this process is not yet elucidated. The present study was designed to investigate the extent of parenchymal chimerism after experimental and clinical gender mismatched liver transplantation. Methods: Rate and frequency of Y-chromosome containing hepatocytes was determined by Fluorescence-in-situ Hybridization (FISH) using a human or rat Y-chromosome specific probe. Biopsy samples from patients after full-size or partial liver transplantation were evaluated. In addition animal experiments were…
Schlagworte
Transplantation
After
Blood
Chimerism
Blood Cells
Biopsy
Zeitschrift für Gastroenterologie
