CareLit Fachartikel

Neutrophil gelatinase-associated lipocalin (NGAL) is a prognostic marker in human primary breast cancer

M Bauer, J Eickhoff, C Mundhenke, N Maass, W Jonat, A Friedl · Geburtshilfe und Frauenheilkunde · 2008 · Heft 09

Dokument
1134714
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Geburtshilfe und Frauenheilkunde
Autor:innen
M Bauer, J Eickhoff, C Mundhenke, N Maass, W Jonat, A Friedl
Ausgabe
Heft 09 / 2008
Seiten
–
Erschienen: 2008-09-12 00:00:00
ISSN
0016-5751

Zusammenfassung

Aims: NGAL is a secreted glycoprotein with proposed functions in proliferation and survival. NGAL is expressed in a variety of tumor types including breast carcinomas. This study examines the relationship between NGAL expression in breast carcinomas and established prognostic markers as well as clinical outcome. Methods: Tissue microarrays were constructed from tumor samples from 207 patients with primary invasive breast cancer. Immunhistochemistry was used to evaluate NGAL expression. Primary endpoints were disease-specific survival (DSS) and disease-free survival (DFS). The associations between NGAL expression…

Schlagworte

NGAL breast cancer prognostic factor Breast Tumor Geburtshilfe und Frauenheilkunde