Potential immunohistochemical markers of tumor vessels in HCC
C Mogler, M Haller, P Schirmacher, T Longerich · Zeitschrift für Gastroenterologie · 2009 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background and objective: Antiangiogenic intervention strategies have become a major issue in modern cancer therapies. Especially in hepatocellular carcinoma (HCC) angiogenesis is of high relevance due to rich vascularisation of the tumor, early access to preexisting vascular network and high angioinvasive property. We therefore evaluated the potential for specific differentiation newly formed tumor capillaries in liver cancer. Methods: We have used a panel of (neo-) vascularization associated markers (CD 276, CD 137, Integrin beta and Tenascin C) on paraffin tissues (Seaman et al., 2007). Slides were additional…