CareLit Fachartikel

Potential immunohistochemical markers of tumor vessels in HCC

C Mogler, M Haller, P Schirmacher, T Longerich · Zeitschrift für Gastroenterologie · 2009 · Heft 01

Dokument
1135131
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
C Mogler, M Haller, P Schirmacher, T Longerich
Ausgabe
Heft 01 / 2009
Seiten
–
Erschienen: 2009-01-20 00:00:00
ISSN
0044-2771

Zusammenfassung

Background and objective: Antiangiogenic intervention strategies have become a major issue in modern cancer therapies. Especially in hepatocellular carcinoma (HCC) angiogenesis is of high relevance due to rich vascularisation of the tumor, early access to preexisting vascular network and high angioinvasive property. We therefore evaluated the potential for specific differentiation newly formed tumor capillaries in liver cancer. Methods: We have used a panel of (neo-) vascularization associated markers (CD 276, CD 137, Integrin beta and Tenascin C) on paraffin tissues (Seaman et al., 2007). Slides were additional…

Schlagworte

CD 276 neoangiogenesis tumor vasculature Tumor Desmin Arteries Actin Zeitschrift für Gastroenterologie