CareLit Fachartikel
Bone-marrow derived Dendritic cells can effectively be pulsed by HBVsvp and induce specific immune reactions in Balb/c mice
M Saad-Farag, B Hoyler, J Encke, W Stremmel, K Weigand · Zeitschrift für Gastroenterologie · 2009 · Heft 01
Dokument
1135137
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Jahr
2009
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Zusammenfassung
Introduction: Chronic Hepatitis B Virus (HBV) infection is a leading cause of liver fibrosis, cirrhosis and development of hepatocellular carcinoma. While virus replication can effectively be controlled by potent new nucleoside and nucleotide analogas, HBs seroconversion, as marker of viral eradication, is achieved very rarely. Therapeutic cell based approaches, like interferon therapy, have a better chance to lead to seroconversion. Dendritic cells (DCs) are key players in the cellular immune response and therefore have a high potential to control or eradicate viral infections. They have been shown to play an i…
Schlagworte
Dendritic cells
HBV
Hepatitis B
subviral particle
Hepatitis
Lead
After
Zeitschrift für Gastroenterologie
