CareLit Fachartikel
Efficacy of switching to Entecavir in chronic HBV patients with low-level replication under Adefovir Dipivoxil
CR Werner, T Bock, B Lutze, S Kaiser · Zeitschrift für Gastroenterologie · 2009 · Heft 01
Dokument
1135138
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Zusammenfassung
Eleven patients with chronic HBV infection (8 HBeAg positive), and persistent viral replication after a mean of 24 months of Adefovir (ADV) monotherapy (range 9–42 months) were switched to Entecavir (ETV) monotherapy either with 0.5 or 1mg daily and retrospectively analyzed for changes in HBV viral load (log10 IU/ml). Mean exposure to ETV was 11.5 months (range 4–24 months). Differences were checked for significance using student’s t-test. The average viral load during the preceding 21 months of ADV therapy was 3.98 (±1.63) log10, the average viral load after switching to ETV was 2.24 (±1.59) log10, thus resulti…
Schlagworte
Adefovir
Entecavir
Hepatitis B
switching
After
Zeitschrift für Gastroenterologie
