CareLit Fachartikel
Interleukin-1ß induces the novel adipokine chemerin in 3T3-L1 adipocytes
G Sommer, S Kralisch, S Weise, U Lössner, M Blüher, M Stumvoll, M Fasshauer · Diabetologie und Stoffwechsel · 2009 · Heft 05
Dokument
1135495
CareLit-ID
Jahr
2009
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Chemerin has recently been characterized as a novel adipokine playing a crucial role in adipocyte differentiation and insulin signaling. In the current study, the impact of insulin resistance-inducing and proinflammatory interleukin (IL)-1ß on chemerin protein secretion and mRNA expression was determined in 3T3-L1 adipocytes. Interestingly, IL-1ß significantly induced chemerin protein secretion almost 1.3-fold from 5.89ng/ml (basal) to 7.52ng/ml (p
Schlagworte
Adipocytes
Adipokine
Phosphatidylinositol 3-Kinase
After
Diabetologie und Stoffwechsel
