The Value of Fetal MRI in the Prediction of Lethal Pulmonary Hypoplasia after Preterm Premature Rupture of Membranes

Purpose: To evaluate the predictive value of MRI volumetry in terms of lethal pulmonary hypoplasia after preterm premature rupture of membranes (pPROM). We hypothesized that with the information obtained by fetal MRI, it would be possible to predict lethal pulmonary hypoplasia. Patients and Methods: This study was a retrospective cohort study in a single large tertiary perinatal referral center including forty-nine fetuses after pPROM, between gestational weeks 16 and 27, who were investigated by MRI lung volumetry. Measured fetal lung volume was expressed as a percentage of the expected lung volume derived from…